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Tear production measurement using phenol red thread tests reveals significantly decreased tear volume in circadian-disrupted mice, consistent with the development of dry eye disease.
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Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development.Cite This Figure
![Figure 3: Tear production measurement using phenol red thread tests reveals significantly decreased tear volume in circadian-disrupted mice, consistent with the development of dry eye disease.]() > Source: Hao Zeng et al. "Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during." *Experimental & molecular medicine*, 2024. PMID: [38956298](https://pubmed.ncbi.nlm.nih.gov/38956298/)
<figure> <img src="" alt="Tear production measurement using phenol red thread tests reveals significantly decreased tear volume in circadian-disrupted mice, consistent with the development of dry eye disease." /> <figcaption>Figure 3. Tear production measurement using phenol red thread tests reveals significantly decreased tear volume in circadian-disrupted mice, consistent with the development of dry eye disease.<br> Source: Hao Zeng et al. "Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during." <em>Experimental & molecular medicine</em>, 2024. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/38956298/">38956298</a></figcaption> </figure>