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[Restless legs syndrome].

Bruno Santos, Ana Sofia Oliveira, Cristina Canhão, Joana Teixeira, Ana Rita Dias et al.
Review Acta medica portuguesa 2008
PubMed
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Study Design

研究タイプ
Review
対象集団
None
介入
[Restless legs syndrome]. None
比較対照
None
主要アウトカム
[Restless legs syndrome].
効果の方向
Mixed
バイアスリスク
Unclear

Abstract

Restless legs syndrome (RLS) is a chronic sensorimotor disorder, with a negative impact in the quality of life and sleep architecture. Despite its reported high prevalence, remains under-recognized and under-treated. The diagnosis is based on the presence of four essential criteria, three supportive clinical features, and other three associated features. The primary or idiopathic RLS is the most common presentation form, but it is very important to exclude other RLS secondary forms and other differential diagnosis. The physiopathology of the idiopathic RLS remains unclear, however changes in the dopamine pathway have been proposed, and justifies the use of dopaminergic agents as first line treatment. Iron therapy, opioids, anti-epileptics (gabapentin) and benzodiazepines are others non-dopaminergic options of treatment in selected patients.

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