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Melatonin for primary insomnia?

Review Drug and therapeutics bulletin 2009
PubMed DOI
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Study Design

Tipo di studio
Review
Popolazione
None
Intervento
Melatonin for primary insomnia? None
Comparatore
None
Esito primario
Melatonin for primary insomnia?
Direzione dell'effetto
Mixed
Rischio di bias
Unclear

Abstract

Melatonin, a hormone produced by the pineal gland, has a key role in regulating circadian rhythms, most importantly, the sleep-wake cycle. Melatonin's action has led to its being tried as a treatment for a wide range of sleep disorders, such as jet lag, primary insomnia, sleep-wake cycle disruption and sleep problems in children with neuro-developmental disorders. Until recently, it had not been licensed in the UK for any indication. Prolonged-release melatonin (Circadin - Lundbeck) has now been licensed as a treatment for primary insomnia. Here we consider whether this product has a place in the management of people with this condition.

TL;DR

Prolonged-release melatonin (▼Circadin – Lundbeck) has now been licensed as a treatment for primary insomnia and it is considered whether this product has a place in the management of people with this condition.

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