Restless legs syndrome.

William G Ondo

Review Current neurology and neuroscience reports 2005 15 citazioni

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Study Design

Tipo di studio: Review
Popolazione: RLS patients

Intervento: Restless legs syndrome. Dopaminergic medications
Comparatore: None
Esito primario: RLS symptom relief
Direzione dell'effetto: Positive
Rischio di bias: Unclear

Abstract

Restless legs syndrome is a very common and still under-diagnosed neurologic condition that can cause severe morbidity. The pathology centers around central nervous system iron homeostatic dysregulation with subsequent alterations in dopaminergic functioning. Genetic studies will hopefully soon identify specific abnormalities. Treatment of restless legs syndrome with dopaminergic medications is highly effective, although augmentation may occur eventually and require dosing flexibility.

TL;DR

Treatment of restless legs syndrome with dopaminergic medications is highly effective, although augmentation may occur eventually and require dosing flexibility.

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Restless legs syndrome.

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Study Design

Abstract

TL;DR

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