Kava and valerian in the treatment of stress-induced insomnia.

D Wheatley

Other Phytotherapy research : PTR 2001 74 citazioni

<\/script>\n

`; }, get iframeSnippet() { const domain = 'sleepcited.com'; const params = 'pmid\u003D11536390'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

Study Design

Tipo di studio: Controlled Clinical Trial
Dimensione del campione: 24
Popolazione: Patients with stress-induced insomnia
Durata: 12 weeks

Intervento: Kava and valerian in the treatment of stress-induced insomnia. Kava 120mg/day (6 wks), then valerian 600mg/day (6 wks)
Comparatore: Baseline comparison
Esito primario: Stress, insomnia, social functioning
Direzione dell'effetto: Positive
Rischio di bias: High

Abstract

Kava and valerian are herbal remedies, claimed to have anxiolytic and sedative properties respectively, without dependence potential or any appreciable side-effects. In this pilot study, 24 patients suffering from stress-induced insomnia were treated for 6 weeks with kava 120 mg daily. This was followed by 2 weeks off treatment and then, 5 having dropped out, 19 received valerian 600 mg daily for another 6 weeks. Stress was measured in three areas: social, personal and life-events; insomnia in three areas also: time to fall asleep, hours slept and waking mood. Total stress severity was significantly relieved by both compounds (p < 0.01) with no significant differences between them; as was also insomnia (p < 0.01). The proportion of patients with no side-effects was 58% with each drug respectively and the 'commonest' effect was vivid dreams with valerian (16%), followed by dizziness with kava (12% ). These compounds may be useful in the treatment of stress and insomnia but further studies are required to determine their relative roles for such indications.

TL;DR

These compounds may be useful in the treatment of stress and insomnia but further studies are required to determine their relative roles for such indications.