Vitamin D
vitaminAlso known as: Cholecalciferol, Vitamin D3
About
Vitamin D is a fat-soluble vitamin with receptors found throughout the brain, including sleep-regulating regions. Research suggests that vitamin D deficiency is associated with shorter sleep duration and poorer sleep quality, and that correcting deficiency may support improvements in sleep.
How It Works
VDR receptors expressed in brainstem sleep-regulating regions; deficiency linked to shorter sleep duration.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| Insomnia | A Strong | 49 | 680771 | View → |
| Sleep Maintenance Insomnia | D Preliminary | 1 | 4552 | View → |
Side Effects
- Hypercalcemia at high doses
- Nausea
- Constipation
- Kidney stones (rare, with excessive intake)
Drug & Supplement Interactions
- Corticosteroids — reduce calcium absorption, affecting vitamin D metabolism
- Weight-loss drugs (orlistat) — may reduce vitamin D absorption
- Statins — vitamin D may affect statin metabolism
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.