Skip to main content
SleepCited
Group Dose (mg/kg) Caffeine (mg/kg) No. falling sleep/total Sleep onset (%) Sleep duration (min) Normal 0 0 6/13 46.15 29.72 ± 2.13a Control 0 10 6/15 40.00 16.40 ± 0.49c GABA 60 10 9/14 64.29 21.55 ± 0.52bc 5-HTP 6 10 8/14 57.14 25.88 ± 1.05ab Combined G
Figure 5. Group Dose (mg/kg) Caffeine (mg/kg) No. falling sleep/total Sleep onset (%) Sleep duration (min) Normal 0 0 6/13 46.15 29.72 ± 2.13a Control 0 10 6/15 40.00 16.40 ± 0.49c GABA 60 10 9/14 64.29 21.55 ± 0.52bc 5-HTP 6 10 8/14 57.14 25.88 ± 1.05ab Combined GABA/5-HTP 66 10 10/15 66.67 26.61 ± 0.01ab Mice received pentobarbital 45 min after the administration of all treatments. Sleep onset (%) = no. falling asleep/total no. × 100. Sleep duration value represents mean ± SE (n = 13-15/group). Different letters indicate significant differences at P< 0.05 by Tukey’s test. GABA, γ-aminobutyric acid; 5-HTP, 5-hydroxytryptophan.

Figure 5

430 × 179px · 9.5 केबी 

Source Paper

Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems.

Nutrition research and practice (2018)

PMID: 29854326

DOI: 10.4162/nrp.2018.12.3.208

Cite This Figure

![Figure 5: Group Dose (mg/kg) Caffeine (mg/kg) No. falling sleep/total Sleep onset (%) Sleep duration (min) Normal 0 0 6/13 46.15 29.72 ± 2.13a Control 0 10 6/15 40.00 16.40 ± 0.49c GABA 60 10 9/14 64.29 21.55 ± 0.52bc 5-HTP 6 10 8/14 57.14 25.88 ± 1.05ab Combined G](https://pdfs.citedhealth.com/figures/29854326/77.png)

> Source: Ki-Bae Hong et al. "Two combined amino acids promote sleep activity in caffeine-induced sleepless mo." *Nutrition research and practice*, 2018. PMID: [29854326](https://pubmed.ncbi.nlm.nih.gov/29854326/)
<figure>
  <img src="https://pdfs.citedhealth.com/figures/29854326/77.png" alt="Group Dose (mg/kg) Caffeine (mg/kg) No. falling sleep/total Sleep onset (%) Sleep duration (min) Normal 0 0 6/13 46.15 29.72 ± 2.13a Control 0 10 6/15 40.00 16.40 ± 0.49c GABA 60 10 9/14 64.29 21.55 ± 0.52bc 5-HTP 6 10 8/14 57.14 25.88 ± 1.05ab Combined G" />
  <figcaption>Figure 5. Group Dose (mg/kg) Caffeine (mg/kg) No. falling sleep/total Sleep onset (%) Sleep duration (min) Normal 0 0 6/13 46.15 29.72 ± 2.13a Control 0 10 6/15 40.00 16.40 ± 0.49c GABA 60 10 9/14 64.29 21.55 ± 0.52bc 5-HTP 6 10 8/14 57.14 25.88 ± 1.05ab Combined G<br>  Source: Ki-Bae Hong et al. "Two combined amino acids promote sleep activity in caffeine-induced sleepless mo." <em>Nutrition research and practice</em>, 2018. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/29854326/">29854326</a></figcaption>
</figure>