Magnesium Glycinate
mineralAlso known as: Magnesium bisglycinate, Magnesium diglycinate
About
Magnesium glycinate is a highly bioavailable form of magnesium chelated with the amino acid glycine. Research suggests it may support relaxation and sleep quality through its role in GABA signaling and the calming properties of glycine itself.
How It Works
GABA receptor agonist and NMDA antagonist; glycinate form provides calming glycine co-benefit for sleep.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| Insomnia | A Strong | 9 | 2998 | Vista → |
| Anxiety-Related Sleep Problems | B Moderate | 1 | 2619 | Vista → |
| Sleep Onset Difficulty | D Preliminary | 0 | -- | Vista → |
| Restless Leg Syndrome | D Preliminary | 0 | -- | Vista → |
Side Effects
- Loose stools or diarrhea
- Nausea
- Abdominal cramping
- Low blood pressure at high doses
Drug & Supplement Interactions
- Antibiotics (tetracyclines, fluoroquinolones) — may reduce absorption
- Bisphosphonates — magnesium may decrease efficacy
- Blood pressure medications — additive hypotensive effects
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.