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Analysis of DNMT1 protein levels and activity in prostate cancer cells treated with melatonin, showing how SIRT1-mediated deacetylation reduces DNMT1 function.
Figure 23
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Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.Cite This Figure
![Figure 23: Analysis of DNMT1 protein levels and activity in prostate cancer cells treated with melatonin, showing how SIRT1-mediated deacetylation reduces DNMT1 function.]() > Source: Lijie Zhou et al. "Melatonin inhibits lipid accumulation to repress prostate cancer progression by ." *Clinical and translational medicine*, 2021. PMID: [34185414](https://pubmed.ncbi.nlm.nih.gov/34185414/)
<figure> <img src="" alt="Analysis of DNMT1 protein levels and activity in prostate cancer cells treated with melatonin, showing how SIRT1-mediated deacetylation reduces DNMT1 function." /> <figcaption>Figure 23. Analysis of DNMT1 protein levels and activity in prostate cancer cells treated with melatonin, showing how SIRT1-mediated deacetylation reduces DNMT1 function.<br> Source: Lijie Zhou et al. "Melatonin inhibits lipid accumulation to repress prostate cancer progression by ." <em>Clinical and translational medicine</em>, 2021. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/34185414/">34185414</a></figcaption> </figure>