What is the recommended dosage for Magnolia Bark?

Sleep: 200-400 mg standardized to 90% honokiol+magnolol

What are the side effects of Magnolia Bark?

Potential side effects include: Drowsiness, Dizziness, Headache, Heartburn.

SleepCited

Magnolia Bark

herb

Also known as: Magnolia officinalis, Honokiol, Magnolol, Relora

About

Magnolia bark extract contains bioactive compounds honokiol and magnolol with demonstrated affinity for GABA-A receptors. Research suggests these compounds may support relaxation and sleep onset through multiple neurological pathways, including GABAergic and cannabinoid receptor modulation.

How It Works

Honokiol is a positive allosteric modulator of GABA-A receptors; magnolol activates cannabinoid receptors.

Evidence For Conditions

Condition	Grade	Studies	Participants
Insomnia	B Moderate	3	723	View →
Anxiety-Related Sleep Problems	C Limited	2	634	View →

Side Effects

Drowsiness
Dizziness
Headache
Heartburn

Drug & Supplement Interactions

Sedatives and alcohol — additive CNS depression
Blood thinners — magnolol may have antiplatelet activity
Antidiabetic drugs — may affect blood glucose levels

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Chamomile Lavender Lemon Balm Passionflower Valerian Root

Quick Facts

Dosage: Sleep: 200-400 mg standardized to 90% honokiol+magnolol
Forms: capsule tablet
Natural Sources: Magnolia tree bark
Upper Limit: Not established
Best Time: 30-60 minutes before bed

Evidence Summary

Insomnia B Moderate

Anxiety-Related Sleep Problems C Limited

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.