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Effects of Ashwagandha (roots of Withania somnifera) on neurodegenerative diseases.

Tomoharu Kuboyama, Chihiro Tohda, Katsuko Komatsu
Review Biological & pharmaceutical bulletin 2014 110 उद्धरण

अध्ययन डिज़ाइन

अध्ययन प्रकार
Review
जनसंख्या
In vitro and in vivo models of neurodegenerative diseases; review of Ashwagandha effects
हस्तक्षेप
Effects of Ashwagandha (roots of Withania somnifera) on neurodegenerative diseases.
तुलनित्र
None
प्राथमिक परिणाम
Effects and mechanisms of Ashwagandha (Withania somnifera) on neurodegenerative diseases (Alzheimer's disease, spinal cord injury) in in vitro and in vivo models
प्रभाव की दिशा
Positive
पूर्वाग्रह का जोखिम
Unclear

सारांश

Neurodegenerative diseases commonly induce irreversible destruction of central nervous system (CNS) neuronal networks, resulting in permanent functional impairments. Effective medications against neurodegenerative diseases are currently lacking. Ashwagandha (roots of Withania somnifera Dunal) is used in traditional Indian medicine (Ayurveda) for general debility, consumption, nervous exhaustion, insomnia, and loss of memory. In this review, we summarize various effects and mechanisms of Ashwagandha extracts and related compounds on in vitro and in vivo models of neurodegenerative diseases such as Alzheimer's disease and spinal cord injury.

संक्षेप में

Various effects and mechanisms of Ashwagandha extracts and related compounds on in vitro and in vivo models of neurodegenerative diseases such as Alzheimer's disease and spinal cord injury are summarized.

साक्ष्य समीक्षाओं में उपयोग किया गया