Melatonin and clinical application.
Studiendesign
- Studientyp
- Review
- Population
- Human subjects across various clinical contexts including sleep disturbance, depression, jet lag, and surgical stress
- Intervention
- Melatonin and clinical application. None
- Vergleichsgruppe
- None
- Primärer Endpunkt
- Sleep quality, circadian rhythm regulation, and clinical applications of melatonin
- Wirkungsrichtung
- Positive
- Verzerrungsrisiko
- Unclear
Abstract
A review of the different publications dealing with melatonin in humans shows that this field has been very active in the last few years. Normative melatonin values have been defined. Various relationships between melatonin and other traits have been studied, such as sleep, circadian rhythm, surgical stress and anaesthesia. Age-related melatonin studies and melatonin during depression and other psychiatric disorders have been reviewed. Finally, some studies have been performed to use melatonin as a medication for sleep disturbance in depression, for jet-lag and as a skin protector for ultraviolet light.
Zusammenfassung
Various relationships between melatonin and other traits have been studied, such as sleep, circadian rhythm, surgical stress and anaesthesia, and some studies have been performed to use melatonin as a medication for sleep disturbance in depression, for jet-lag and as a skin protector for ultraviolet light.