Effects of Ashwagandha (roots of Withania somnifera) on neurodegenerative diseases.
研究设计
- 研究类型
- Review
- 研究人群
- In vitro and in vivo models of neurodegenerative diseases; review of Ashwagandha effects
- 干预措施
- Effects of Ashwagandha (roots of Withania somnifera) on neurodegenerative diseases.
- 对照组
- None
- 主要结局
- Effects and mechanisms of Ashwagandha (Withania somnifera) on neurodegenerative diseases (Alzheimer's disease, spinal cord injury) in in vitro and in vivo models
- 效应方向
- Positive
- 偏倚风险
- Unclear
摘要
Neurodegenerative diseases commonly induce irreversible destruction of central nervous system (CNS) neuronal networks, resulting in permanent functional impairments. Effective medications against neurodegenerative diseases are currently lacking. Ashwagandha (roots of Withania somnifera Dunal) is used in traditional Indian medicine (Ayurveda) for general debility, consumption, nervous exhaustion, insomnia, and loss of memory. In this review, we summarize various effects and mechanisms of Ashwagandha extracts and related compounds on in vitro and in vivo models of neurodegenerative diseases such as Alzheimer's disease and spinal cord injury.
简要概述
Various effects and mechanisms of Ashwagandha extracts and related compounds on in vitro and in vivo models of neurodegenerative diseases such as Alzheimer's disease and spinal cord injury are summarized.