Tryptophan
amino_acidAlso known as: L-Tryptophan
About
Tryptophan is an essential amino acid that serves as the precursor to serotonin and subsequently melatonin. Research suggests supplementation may support sleep onset by increasing the availability of these sleep-related neurotransmitters in the brain.
How It Works
Essential amino acid precursor to serotonin and melatonin via tryptophan hydroxylase and AADC pathway.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| Insomnia | A Strong | 75 | 32701 | View → |
| Sleep Onset Difficulty | B Moderate | 19 | 96 | View → |
Side Effects
- Nausea
- Diarrhea
- Drowsiness
- Dry mouth
- Blurred vision
Drug & Supplement Interactions
- SSRIs/SNRIs — risk of serotonin syndrome
- MAOIs — dangerous serotonin accumulation
- Sedatives — additive drowsiness
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.