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Distribution of 5-HT receptor subtypes in brain regions involved in seizure generation. The high density of 5-HT1A receptors in the hippocampus aligns with cannabidiol's observed efficacy in temporal lobe epilepsy models.
Figure 149
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Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Seizures and Epilepsy.Cite This Figure
![Figure 149: Distribution of 5-HT receptor subtypes in brain regions involved in seizure generation. The high density of 5-HT1A receptors in the hippocampus aligns with cannabidiol's observed efficacy in temporal lobe epilepsy models.]() > Source: Lara Senn et al. "Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Se." *Pharmaceuticals (Basel, Switzerland)*, 2020. PMID: [32751761](https://pubmed.ncbi.nlm.nih.gov/32751761/)
<figure> <img src="" alt="Distribution of 5-HT receptor subtypes in brain regions involved in seizure generation. The high density of 5-HT1A receptors in the hippocampus aligns with cannabidiol's observed efficacy in temporal lobe epilepsy models." /> <figcaption>Figure 149. Distribution of 5-HT receptor subtypes in brain regions involved in seizure generation. The high density of 5-HT1A receptors in the hippocampus aligns with cannabidiol's observed efficacy in temporal lobe epilepsy models.<br> Source: Lara Senn et al. "Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Se." <em>Pharmaceuticals (Basel, Switzerland)</em>, 2020. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/32751761/">32751761</a></figcaption> </figure>